Clinical Trials

I may have posted this before but it seemed worth revisiting. If you are looking for clinical trials related to ASDs, check out

www.clinicialtrials.gov

Here is a sampling on a search "autistic disorder".

Smart is not an Endgame

Penelope Trunk reminds us to pay attention to social skills - our own and our children's.

"And when you think about someone finding his way to success in the real world, consider the Wall Street Journal's list of traits that recruiters look for in business school candidates:
• Communication and interpersonal skills
• Original and visionary thinking
• Leadership potential
• Ability to work well on a team
• Analytical and problem-solving skills"

Test

Just testing out a change made nervously to my template. I am such a blog design coward!

Article on RDI

This article by Mary Jiminez from the Shreveport Times (Louisiana) describes one family's experience with RDI - Relationship Development Therapy. The price tag is $500-$800 per month, and it is not covered by insurance.

Autistic Brain Structure & Development

Wrongplanet posts an interesting article from the journal Neuron about the size of portions of brains in autistic children and autistic adults.

"Surprisingly, current research is showing different results in the brains of autistic children compared to data collected in adults. The very same structures that appear smaller in adult autistic brains appear much larger and overgrown in autistic children. "

This paragraph is kind of shocking:
"Considerations for developmental aspects of autism are becoming ever more important. Even gene-association studies may be inconsistent because the genes that cause and regulate differential development may not be the same as those genes that respond to these differences later in life, making it hard to define a clear set of “autism” genes. This means, that genes found in autism studies may be identifying genes involved with secondary issues and are not finding genes that have to do with developing autism directly. Indeed, many genes identified thus far in autistic patients have to do with regulating cell death in the brain and may only be expressed secondarily in response to the overgrowth of particular brain structures."

Contestant with AS on "America's Top Model"

Aspiring model Heather Kuzmich made it to the Top 5 on the current edition of "America's Top Model." Heather, has Asperger's Syndrome, and her experience is described in this article. I'm sorry I missed this. If anyone did watch it, please comment with your thoughts.

AS and Sleep

This should come as no surprise to parents of children with Asperger's. But at least they are studying it.
" The first known attempt to evaluate the sleep patterns of children with Asperper Syndrome (AS), taking into account sleep architecture and the cyclic alternating pattern (CAP), finds that children with AS have a high prevalence of some sleep disorders and mainly problems related to initiating sleep and sleep restlessness together with morning problems and daytime sleepiness, according to a new study."

Bush Vetoes Funding Bill for Combating Autism Act

From the Autism Society of America Web site:
"On November 13, President Bush vetoed the FY 2008 Labor, Health and Human Services and Education Appropriations bill. This bipartisan bill had strong support in both the House and the Senate, but the President objected to the overall funding levels of the bill, which includes modest increases for vital programs - most of which have experienced significant cuts, lost purchasing power or both over the past three years.
This legislation includes significant increases for autism programs at the Centers for Disease Control and Prevention (CDC), the Health Resources and Services Administration and the National Institutes of Health. These increases represent full funding of the Combating Autism Act, and are critical in improving our ability to diagnose, intervene and develop new therapies for autism. We need this crucial investment!
The House could move to override the President’s veto as early as this week. Contact your Member of Congress and urge them to vote YES on the veto override.
Click here to take action now."

NJ Theater Workshop for Adults with Autism

From Tina Kelley, reported in the New York Times, an article about a 12 week theater workshop at Montclair State University.
"B. Madeleine Goldfarb, the director of outreach and education at the Autism Center, helped get funding for the program. She said of the center’s clients: “Most of them have some sort of passion for something, and can be savantlike within that particular passion. How do you harness that?”
Ms. Goldfarb, who is pursuing more grants for the program, described its roots in discussions with some of the center’s clients.
“They were all sitting in their own little worlds, not communicating with one another around a big conference table, not making eye contact or engaging,” she said. She asked them what their passions were, and the atmosphere quickly became charged as a consensus grew around theater.
“There was a change in connectedness, in reciprocity, in giving suggestions, with other people in the room commenting on suggestions,” she said. “It was astounding.”
By welcoming adults, the workshop fills a crucial need. Suzanne Buchanan, the director of clinical services at the New Jersey Center for Outreach and Services for the Autism Community, described “almost a total lack of funding of appropriate programs” for adults with autism, many of whom do not work full time.
“Having a meaningful activity where they’re working productively with others, working toward a common goal, is a really great way for them to spend their time,” Dr. Buchanan said.

AAP Reports

The American Academy of Pediatrics just published two new reports related to ASDs. Although they are written for clinicians, they are sure to have useful information for families.

The first is called "Identification and Evaluation of Children with Autism Spectrum Disorders".
It describes signs and symptoms for pediatricians.
The second is "Management of Children with Autism Spectrum Disorders". According to the press release, this report "strongly advises intervention as soon as an ASD diagnosis is seriously considered rather than deferring until a definitive diagnosis is made. The child should be actively engaged in intensive intervention at least 25 hours per week, 12 months per year with a low student-to-teacher ratio allowing for sufficient one-on-one time. " The press release also says, "Pediatricians who treat children with ASDs should recognize that many of their patients will use nonstandard therapies. The report says it’s important for pediatricians to become knowledgeable about complementary and alternative medicine (CAM) therapies, ask families about current and past CAM use, and provide balanced information and advice about treatment options, including identifying risks or potential harmful effects. They should avoid becoming defensive or dismissing CAM in ways that convey a lack of sensitivity or concern, but they should also help families to understand how to evaluate scientific evidence and recognize unsubstantiated treatments. "

Disclosure

This article by Debi Boucher Stetson in a New England newspaper, touches on a sticky subject: what and whom to tell about your child's special needs.

Facilitated Communication

This blog post from Dr. Sanjay Gupta at CNN triggers some interesting comments on Facilitated Communication.

Clinton Asked About Autism

Just a blurb that came my way. Posted by Mark Murray on an MSNBC News blog called "First Read":
"[Hillary} Clinton answered questions from voters at a town hall at the opera house here, which was her second stop on a two-day swing through the state...Other audience members asked...what she would do to address disorders like Asperger's syndrome, which is part of the autism spectrum of disorders. Clinton responded ...that she wanted to be the president to put autism on the map and help families dealing with it. ."

Thimerosal Study

Here is a link via Robert Bazell in The Daily Nightly that leads to the full-text article in The New England Journal of Medicine "Early Thimerosal Exposure and Neuropsychological Outcomes at 7 to 10 Years". I don't know how long it will be available for free online.

NJ Father Wins Lawsuit for Son's Care

I heard the teaser for this story by Larry Abramson on NPR, but missed the broadcast. It is now available live online.
"What they said when they rejected me was that treatment was not restorative. It didn't restore a previously existing function," Micheletti says. "Jake was three and a half. He had never spoken before. [The insurance company thought], 'Why should we give him verbal behavior therapy to make him speak now.'"

Autism in Girls

I missed this article from August 5th's New York Times Magazine by Emily Bazelon on autism in girls. It's heartbreaking in its description of the social isolation and depression that girls on the spectrum might be in greater danger of suffering, simply becasue social connections are so important to girls' self-esteem and social awkwardness is a more acceptable male trait.

"Because there are so many fewer females with autism, they are “research orphans,” as Ami Klin, a psychology and psychiatry professor who directs Yale's autism program, puts it. Scientists have tended to cull girls from studies because it is difficult to find sufficiently large numbers of them. Some of the drugs, for example, commonly used to treat symptoms of autism like anxiety and hyperactivity have rarely been tested on autistic girls. "

"No doubt part of the problem for autistic girls is the rising level of social interaction that comes in middle school. Girls’ networks become intricate and demanding, and friendships often hinge on attention to feelings and lots of rapid and nuanced communication — in person, by cellphone or Instant Messenger. No matter how much they want to connect, autistic girls are not good at empathy and conversation, and they find themselves locked out, seemingly even more than boys do."

Contagious Yawning

Fron Mindhacks come this study published by the British Psychological Society that claims that people with ASDs are immune to contagious yawning.
"Past research has found that seeing the eye region of someone yawn is key to the yawn's contagious effects. So perhaps the fact that people with autism are known to focus more on the mouth region of people's faces, rather than the eyes, could partly explain the current findings.Atsushi Senju and colleagues said their results “support the claim that contagious yawning and the capacity of empathy share common neural and cognitive mechanisms.' "

Oprah TODAY

Tuesday's (9/18/07) episode of The Oprah Winfrey Show (CBS) will be about Autism.
Actresses Jenny McCarthy and Holly Robinson Peete will guest. (Thanks, ASPENNJ Ocean County!)

New Baron-Cohen Study Links Autistic Traits to Testosterone

From a story in the Telegraph of the United Kingdom by Nic Fleming and Roger Highfield"
"Professor Simon Baron-Cohen, from Cambridge University, one of the world's leading experts on autism, revealed initial details of his new study at the British Association Festival of Science in York yesterday.
Professor Baron-Cohen said: "The idea that fetal testosterone may play a causal role in autism is an existing hypothesis.
"There's no evidence that it's a causal factor, but this research is certainly consistent with that hypothesis."

The Urge to Label

When I started reading this article in Newsweek by Lorraine Ali, I thought it was bashing "overdiagnosis" of ASDs. But then I came upon this paragraph:
"... Mary-Dean Barringer, of the nonprofit learning institute All Kinds of Minds, says we put too much emphasis on the labels that others assign to our kids. "We're absolutely appalled by this diagnosis of Asperger's syndrome," says Barringer. (Asperger's is a high-functioning form of autism, marked by obsessive interests and impaired social interaction.) "These are very highly specialized minds, and to put a syndrome on it and treat it as an aberration does damage to kids and families. There are still challenges there on how to manage it, but why not call it a highly specialized mind phenomenon rather than a disorder? That label alone shapes public perception about uniqueness and quirkiness." "